Structural studies of RecF
نویسندگان
چکیده
منابع مشابه
Structural conservation of RecF and Rad50: implications for DNA recognition and RecF function.
RecF, together with RecO and RecR, belongs to a ubiquitous group of recombination mediators (RMs) that includes eukaryotic proteins such as Rad52 and BRCA2. RMs help maintain genome stability in the presence of DNA damage by loading RecA-like recombinases and displacing single-stranded DNA-binding proteins. Here, we present the crystal structure of RecF from Deinococcus radiodurans. RecF exhibi...
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Homologous, or general, recombination is a crucial biological process that involves the paring and transfer of strands between DNA molecules that share a region of significant sequence homology. After its discovery in 1946 by Lederberg and Tatum (48), homologous recombination in bacteria was associated with the sexual process of conjugation and was viewed as an evolutionary mechanism both for s...
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Structural studies on the interaction of nano-SiO2 with lysozyme
The interaction between nano-SiO2 and lysozyme was investigated by the method of UV-Visible detection and fluorescence spectroscopic techniques. The thermal denaturation of lysozyme has been investigated in the presence and absence of nano-SiO2 over the temperature range (293-373) K in different buffers and pH values, using temperature scanning spectroscopy. The presence of nano-SiO2 caused th...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2008
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.22.1_supplement.591.6